At the end of the day, uremia still favors these eight common kidney diseases

2022-06-17 0 By

Zhou Xun, director of nephrology physicians found that he suffered from kidney disease, many kidney friends always worry about which day will develop into uremia.In fact, there is no need, from the big data, the proportion of chronic kidney disease (CKD) eventually progress into uremia is only less than 2%, it can be said that the vast majority of kidney disease will not progress into uremia.However, as the total number of people with CKD in China is close to 130 million, the number of uremia developed from this is relatively large.Therefore, it is still necessary to attract the attention of renal friends, among which early detection and standardized treatment is the key.Speaking of here, should say that more kidney friends are concerned about which kidney disease is easy to develop into uremia?From the data coming out of the blood purification center, uremia favor or the following eight common kidney disease.1. The urine protein, not of primary nephrotic syndrome of the pathological types of primary nephrotic syndrome can be characterized by small lesion, membranous nephropathy, mesangial proliferative glomerulonephritis and membrane hyperplastic nephritis, etc, almost all the small lesions, the vast majority of membranous nephropathy and mesangial proliferative glomerulonephritis, and a few hyperplastic nephritis patients with urinary protein membrane is able to come down,And it can go down to the normal range.Therefore, these primary nephrotic syndromes with treatable remission are unlikely to develop into uremia.Only a few membranous nephropathy with low urinary protein, moderate and severe mesangial proliferative nephritis and most membranous proliferative nephritis are easily targeted by uremia.Standardized use of hormones and immunosuppressants can greatly reduce the incidence of uremia.2. Urine protein is far more than standard IgA nephropathy. Due to the high incidence of IgA nephropathy, there are more uremia developed from IgA nephropathy.IgA nephropathy is less likely to develop into uremia if the 24-hour urine protein level can be reduced to 0.3 g and blood pressure can be controlled.If the 24-hour urine protein level of patients with IgA nephropathy is always more than 0.5-0.8 g, or even more than 1.0 g, or combined with high blood pressure, IgA nephropathy is easy to be targeted by uremia.Long-term use of sartan or Pulpric drugs is a good choice to avoid uremia.3. The inflammatory state has always been the existence of the existence state of inflammation with lupus nephritis is a major exception activity with lupus nephritis, in addition to “lupus” related indices abnormal, often also can appear the urine protein significantly overweight, and 24 hours urinary protein quantitative long-term more than 1.0 grams with lupus nephritis often exist the inflammatory state, it is a kind of nephritis uremia easy to favor.To keep lupus nephritis under control, patients still need to take small doses of glucocorticoids over a long period of time to suppress the inflammatory state, which can to some extent prevent progression to uremia.Chronic pyelonephritis is mostly caused by bacterial infection, which is also an important cause of chronic renal failure and uremia. Easy recurrence is an important contributing factor, which is related to the existence of recurrent bacterial infection.Reduced resistance, poor hygiene, a dislike of water and irregular antibiotic use are all causes or triggers of recurrent infections.Avoiding the chance of infection and active anti-infection treatment can reduce the risk of uremia, and chronic pyelonephritis can not be targeted by uremia.Chronic tubulointerstitial nephritis (TUbulointerstitial nephritis) is also a cause of uremia. Chronic tubulointerstitial nephritis (TUbulointerstitial nephritis), including analgesic nephropathy, is associated with the use of nephrotoxic drugs.Antipyretic and pain-relieving agents, aminoglycoside antibiotics, various contrast agents and traditional Chinese medicine and patent medicine containing aristolocholic acid can all cause interstitial nephritis. If these nephrotoxic drugs continue to harm the kidneys, uremia is more prone to this type of nephropathy.By keeping nephrotoxic drugs out of the kidneys, uremia can be prevented in the future.Polycystic kidney disease polycystic kidney disease is the type of kidney disease most likely to develop into uremia.However, prior to uremia, POLYcystic kidney disease is often silent and can be without obvious discomfort.If no one in the family has POLYcystic kidney disease, patients do not think of going to the hospital to have their kidneys checked.If a family member has POLYcystic kidney disease, the patient also needs a doctor’s warning to go to the hospital for kidney tests.If it is detected early and measures are taken (such as lowering blood pressure, preventing infection and controlling diet), it can continue its development.Nowadays, the chronic renal insufficiency and uremia gradually developed from primary hypertension have been more and more, the main reason is that the patient’s blood pressure is always down or failed to control the standard.Essential hypertension mainly harms the heart, brain, kidney and other important target organs, among which the kidney damage is called hypertensive nephropathy.Early use and standard use of antihypertensive drugs, and adhere to a low-salt diet and lifestyle adjustment, blood pressure can be controlled to standard, uremia will not favor this kind of patients.8. The diabetic nephropathy that has been dragged to the advanced stage is not believed. If it is still in the early stage before the third stage, active treatment and management (such as blood pressure control, early use of sartan or Pulliform drugs and change of lifestyle and eating habits, etc.), the diabetic nephropathy complicated by diabetes is hopeful to reverse.However, if it has advanced to stage 4 or 5, it is difficult to prevent the progression of chronic renal failure and uremia, even with treatment.Therefore, early treatment and standardized treatment is the key to prevent diabetic nephropathy from developing into uremia.Advanced diabetic nephropathy, more likely to be targeted by uremia.Conclusion: the above eight kinds of kidney disease patients need early treatment and standard treatment, so as to avoid or delay the development of uremia.With the same name “kidney first” wechat public number synchronously first, the article for Zhou Xun original, shall not be reproduced without authorization.